Friday, December 27, 2013

Age & Breast Cancer Risk

Age & Breast Cancer Risk

There are a number of risk factors associated with breast cancer. Certain risk factors, such as being overweight or consuming alcohol, can be changed. Other breast cancer risk factors are inevitable or irreversible, however. One such example is age, which plays a significant role in a woman's risk of developing breast cancer.

The Facts

    The risk of breast cancer increases with age. According to the Illinois Department of Public Health, 80 percent of women who are diagnosed with breast cancer are over the age of 50. Many women with breast cancer tend to be over 60. Breast cancer also becomes harder to treat among older women. The American Cancer Society reports that two out of three breast cancer cases in woman over age 55 are invasive, compared to one in eight among women under age 40.

Other Age-Related Factors

    The age a woman is when she reaches menstruation and menopause or has a baby can affect her risk of developing breast cancer. According to the U.S. Department of Health & Human Services, women who begin menstruating before age 12 and start menopause after 55 are at an increased risk. Having a baby before the age of 20 decreases the risk of breast cancer.

Considerations

    Although age plays a prominent role in the development of breast cancer, it is important to keep in mind that a woman can be diagnosed at any age. There are young women who become diagnosed with breast cancer. Age is not the only risk factor of breast cancer. Women with a family history of breast cancer, especially if the cancer was diagnosed under the age of 40, are at an increased risk.

Prevention

    Women who are older may be at a greater risk of other risk factors of breast cancer. According to the U.S. Department of Health & Human Services, obese women who have gone through menopause without using hormone therapy are more likely to experience breast cancer. Exercising for more than four hours per week and following a healthy diet can help decrease a woman's chances of developing breast cancer.

Detection

    According to the American Cancer Society, women should begin having yearly mammograms at age 40. Women who have a family history of breast cancer are generally recommended to begin having mammograms in their early to mid-30s, however. In some cases, they may even begin in their late 20s. Early screening is especially important if the women in their family were diagnosed before they were 40 years old. Women in their 20s and 30s should have yearly clinical breast exams.



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    www.ncbi.nlm.nih.gov Journal List NIHPA Author Manuscripts

    Approximately 7% of women with breast cancer are diagnosed before the age of 40 years, and this disease accounts for more than 40% of all cancer in women in this age ...


  • Susan G. Komen Understanding Breast Cancer Risk Factors

    ww5.komen.org/BreastCancer/GettingOlder.html

    Age is a well-established risk factor for breast cancer. The older a woman is, the more likely she is to develop the disease. In general, rates of breast cancer are ...

  • Breast cancer risk factors : Cancer Research UK

    www.cancerresearchuk.org/cancer-info/cancerstats/types/breast...

    This page contains information on breast cancer risk. A substantial proportion of the breast cancer cases experienced in developed countries can be explained by ...


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    Breastcancer.org is a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer.


  • Definite breast cancer risks : Cancer Research UK : CancerHelp

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    Definite breast cancer risks. Researchers have identified a number of things that can affect your risk of breast cancer. Breast cancer risk increases with age.


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    envirocancer.cornell.edu

    The Program on Breast Cancer and Environmental Risk Factors at Cornell University provides science-based information on breast cancer and environmental risk factors.

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    An interactive tool designed by scientists at the National Cancer Institute and the NSABP to estimate a woman's risk of developing invasive breast cancer.


  • Breast cancer - Wikipedia, the free encyclopedia

    en.wikipedia.org/wiki/Breast_cancer

    Breast cancer is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk.


  • Breast Cancer Risk Assessment Tool

    www.cancer.gov/bcrisktool

    An interactive tool designed by scientists at the National Cancer Institute and the NSABP to estimate a woman's risk of developing invasive breast cancer.

  • Breast Cancer Risk Prediction Models - EGRP

    epi.grants.cancer.gov/cancer_risk_prediction/breast.html

    Breast Cancer Risk Prediction Models. Absolute Risk Prediction Models; Gene Carrier Status Risk Prediction Models; Risk Prediction Models of Women at High Risk


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    Overview. Every woman is at risk for breast cancer and her risk increases with age. A woman in the general population faces about a 13% lifetime risk of developing ...


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    1. Am J Hum Genet. 2003 May;72(5):1117-30. Epub 2003 Apr 3. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case ...


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    Email to a friend. All Topics Forum: High Risk for Breast Cancer Forum: High Risk for Breast Cancer. Due to family history, genetics, or other factors.


  • Breast Cancer Prevention, Treatment and Survival

    breastcancer.about.com

    Salmon, sardines, tuna, mackerel and herring - all of these fish are rich in oils that could knock your risk for breast cancer down by 14% below average.


  • Breast cancer risk factors Breakthrough Breast Cancer

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    Find out about the established risk factors which can cause breast cancer

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    Who is at risk for breast cancer? Women with certain medical conditions, lifestyle habits, or traits (referred to as risk factors) may be more likely ...


  • Breast cancer

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    Many studies have shown that women with breast cancer are at a 3-to 4-fold increased risk of developing a new primary cancer in the opposite breast.

  • Breast Cancer Surveillance Consortium

    breastscreening.cancer.gov

    Items of Interest; Mammogram Every Two Years Has Same Benefit as Yearly Mammogram for Older Women, UCSF Study Finds. Yearly test leads to more false


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    Staying at a healthy weight, being physically active, and limiting how much alcohol you drink can help reduce your risk of breast cancer. Regular screening can often ...

  • Breast Cancer Risk Reduction: Can Breast Cancer Be "Prevented"?

    ezinearticles.com/?Breast-Cancer-Risk-Reduction:-Can-Breast-Cancer...

    Feb 16, 2012 Virtually all women have fears about developing breast cancer; for women that have already been diagnosed with breast cancer in the past, there is ...

  • Am I at risk? Breast Cancer Care

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    Because we are all different, any of the known associated risk factors will not affect us all in the same way. Identifying the cause of breast cancer to one specific ...

  • Susan G. Komen Understanding Breast Cancer Risk Factors

    ww5.komen.org/BreastCancer/MenopauseatAge55orOlder.html

    Going through menopause at a late age is a well-established risk factor for breast cancer. Studies show that women who go through menopause after age 55 have

  • GenomicsResourcesDiseasesBreast and Ovarian CancerFamily ...

    www.cdc.gov Genomics Genomic Resources Diseases

    May 16, 2013 Genomics and Health Breast and Ovarian Cancer and Family History Risk Categories

  • Breast Cancer Symptoms: lumps, swelling or skin changes can be ...

    www.breastcancer.org/symptomTypes of Breast Cancer Breast Self-Exam Your Diagnosis Mammograms

    Breast cancer symptoms and diagnostic tests as well as information on types of breast cancer.

Wednesday, December 25, 2013

Stage 2 Breast Cancer Treatments

Factors that determine breast cancer stage include the size of the tumor, whether the cancer has spread to other parts of the body, whether the cancer is invasive and whether the lymph nodes have been affected. Determining the stage of breast cancer helps healthcare professionals provide patients with the most effective treatment options. For instance, stage II breast cancer treatments will differ from patients who are diagnosed with a level III or IV.

Defining Stage II Breast Cancer

    According to BreastCancer.org, stage II breast cancer is divided into two subcategories known as IIA and IIB:

    There are three different scenarios that are considered stage IIA breast cancer:

    1.An invasive breast cancer in which cancer cells are identified in the lymph nodes under the arm (axillary lymph nodes), but there is not an actual tumor in the breast.
    2.A tumor in the breast that is smaller than two centimeters, but has already spread to the axillary lymph nodes.
    3.A tumor that is between two and five centimeters wide that has not yet spread to the axillary lymph nodes.

    Stage IIB breast cancer is used to describe either:

    1.A tumor that is between two and five centimeters and has made its way to the axillary lymph nodes.
    2.A tumor that has not yet spread to the axillary lymph nodes, but is at least five centimeters wide.

Stage II Breast Cancer Treatment Options

    Women with stage II breast cancer will most likely undergo surgery followed by radiation and chemotherapy. Because no two women are the same, however, every case of breast cancer, even those falling into the same stage, will differ. Thus, there is not one specific treatment designed for patients with stage II breast cancer.

    In most cases, according to WebMD, a combination of treatments will likely be used to battle stage II breast cancer. Following are the most common treatment options.

Surgery

    According to WebMD, because the cancer in stage II tends to be contained to the breast and, in the worst cases, its nearby lymph nodes, most women with this type of breast cancer will undergo surgery. Depending on the size of the tumor, there are two types of surgery used to treat stage II breast cancer:

    1.Lumpectomy: A breast-conserving procedure in which the tumor and some of the surrounding breast tissue is removed without misshaping the breast.

    2.Mastectomy: Historically, when a mastectomy was performed the entire breast was removed. Today, there are other types of mastectomy designed to be less invasive. The type of mastectomy will depend on the size of the tumor and other factors such as the patient's age, overall health and menopause status.

Radiation Therapy

    Most lumpectomies are performed in conjunction with radiation therapy. Radiation therapy is used to kill cancer cells that survive surgery. In some cases, radiation will also be administered to patients following a mastectomy.

Chemotherapy

    Chemotherapy describes treatment with cancer fighting drugs. In most cases, women with stage II breast cancer will be treated with chemotherapy in combination with surgery and radiation. The drugs are designed to kill any undetected cancer cells that may have spread to other areas of the body. Chemotherapy may also be used to shrink a tumor before surgery.

Hormone Therapy

    Hormone therapy is designed to prevent the body from producing naturally occurring estrogen in women whose tumors contain estrogen receptors (ER-positive). This type of cancer feeds on the body's natural production of estrogen. Doctors will likely prescribe oral pills that will block the body from producing estrogen.

Biological Therapy

    According to WebMD, one of the newest treatments for stage II breast cancer is called biological therapy. This treatment is designed specifically for women with an excessive amount of the protein, HER2, which causes cancer to spread at a rapid rate. WebMD claims that about 25 percent of women with breast cancer have an excess of HER2. Biological therapy uses Herceptin, a drug designed to prevent the protein from feeding the cancer. In many cases, this stage II breast cancer treatment will be used in conjunction with chemotherapy because Herceptin is said to help advance the effectiveness of chemotherapy.


  • Breast Cancer Survival Rate - Stage 2 Breast Cancer

    ezinearticles.com/?Breast-Cancer-Survival-Rate---Stage-2-Breast...

    Aug 21, 2007 The breast cancer survival rate for Stage 2 breast cancer can vary from 76% to 92% in the U.S. Here are statistics to help you understand the reasons for ...

  • Stage 3 Colon Cancer Treatment

    stage-3-colon.cancertreatment.net

    Since in Stage 3 colon cancer, the cancer has spread to nearby lymph nodes, but not yet to other parts of the body surgery is recommended followed by chemotherapy.


  • Stage 1 Breast Cancer Treatment

    stage-1-breast.cancertreatment.net

    Typical Stage 1 breast cancer treatment options may include surgery and hormone therapy. Stage 1 breast cancer is defined as being small in size (tumor/cancerous ...

  • Stage 4 Breast Cancer Treatment

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    Stage 4 breast cancer treatment options are for Stage 4 breast cancer, where the cancer has spread beyond the breast and lymph nodes to other parts of the body.

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    Stage I, II, IIIA, and Operable IIIC Breast Cancer. Primary Therapy Local-regional treatment Axillary lymph node surgery

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    www.ncbi.nlm.nih.gov Taylor & Francis iOpenAccess

    Aug 05, 2011 This review concerns the effects on vision and the eye of medications prescribed at three phases of treatment for women with early-stage breast cancer

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    Breastcancer.org is a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer.

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    en.wikipedia.org/wiki/Breast_cancer

    Breast cancer is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk.


  • Stage 2 Breast Cancer Treatment

    stage-2-breast.cancertreatment.net

    Stage 2 breast cancer treatment options may include chemotherapy, radiotherapy and hormone therapy.


  • Breast Cancer Survival Rate - Stage 4 Breast Cancer

    ezinearticles.com/?Breast-Cancer-Survival-Rate---Stage-4-Breast...

    Aug 25, 2007 The 5-year breast cancer survival rate for Stage 4 breast cancer is very low compared to breast cancer detected at earlier stages. Here is some basic ...

  • Stage IV life expectancy? - Prognosis - Breast Cancer

    www.healthcentral.com Breast Cancer Diagnosis Prognosis

    I have a friend who is Stage IV breast cancer. This is her second round with cancer. She has lobular carcinoma. She is Stage IV. The tumors are on her spine, hi...

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    CancerTreatment.net is an online resource that lists Cancer Treatment Options for patients, families and friends.

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    stage-3-colon.cancertreatment.net

    Since in Stage 3 colon cancer, the cancer has spread to nearby lymph nodes, but not yet to other parts of the body surgery is recommended followed by chemotherapy.

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    Expert-reviewed information summary about the treatment of breast cancer.

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    Since in Stage 4 colon cancer, the cancer has spread from the colon to distant organs such as the liver, lungs or ovaries, surgery is not typically performed in order ...


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    Welcome to breast cancer information! Here is information for newly diagnosed breast cancer patients, family members or supportive friends. Learn how to lower your ...


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    Cancer staging is the process of determining the extent to which a cancer has developed by spreading. Contemporary practice is to assign a number from I-IV to a ...

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    Breast Cancer Discussion Forums - Access the shared knowledge of thousands of people affected by breast cancer

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    Prostate cancer that has been diagnosed as Stage 4 is a large tumor that has spread beyond the prostate to organs such as the bladder or rectum, the lymph nodes or ...

  • Breast Cancer Stage IV w/ Bone and Liver Metastases - YouTube

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    Lucia Lizotte. After 8 months of Issels Treatment bone metastases of sternum disappeared and 4 of 5 liver metastases gone. February 2008, Lucia in her own ...


  • Stage 4 Breast Cancer Testimony - YouTube

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    Dr. Carrie Miller discusses the case of patient with stage 4 breast cancer. This is another story of a woman and a family that would not give up or give in ...

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    Learn about treatment for different stages of colorectal cancer.


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How Is Breast Cancer Inherited?

Identification

    While breast cancer has many risk factors, such as age and lifestyle factors such as smoking, there also is a genetic component to breast cancer. Scientists have pinpointed genes, such as mutations of the BRCA1 and BRCA2 genes, which have been shown to contribute to the development of breast cancer. The BRCA genes are known as supressor genes, meaning that, when intact, they suppress cell growth that can lead to breast cancer.

Mutation

    While in most people the BRCA1 and BRCA2 genes work to prevent cell growth, genetic mutations can keep the gene from doing its job of suppressing cell growth. Heredity is one way in which a person can have an "injured" BRCA1 or BRCA2 gene from birth, whereas other breast cancers may be due to genes that are damaged due to other causes.

Family History

    Every person, male and female, carries the BRCA1 and BRCA2 genes. However, in those with a family history of breast cancer, the risk is increased that the parents will pass the gene along to their offspring. If only one parent has the injured gene, there is a 50 percent chance the offspring will have an injured gene, according to BreastDoc.com. If both parents carry the mutation, there is a 100 percent chance the offspring, male or female, will have the mutation.

Not an Absolute

    Women or men who have the gene mutation do not always get breast cancer. However, they are considered to be at an especially heightened risk compared with those who do not. Another consideration is that the person who carries this gene also runs the risk of passing it down to her offspring. While estimates vary, anywhere from 5 to 27 percent of breast cancers occur as a result of hereditary traits, according to the National Human Genome Research Institute.

    Certain cultures are shown to have a higher likelihood for carrying the BRCA1 and BRCA2 genetic mutations. These include Ashkenazi Jews, as well as people from Norway and Iceland, according to the National Human Genome Research Institute.

    A hereditary test for breast cancer exists. However (as previously mentioned) this test does not always mean a person will or will not get breast cancer. However, it may help in decision making, particularly in the instance of family planning.


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    en.wikipedia.org/wiki/Breast_cancer

    Breast cancer is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk.


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    Breastcancer.org is a nonprofit organization dedicated to providing the most reliable, complete, and up-to-date information about breast cancer.


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    As Kimberly Banks explains, the genetic test typically costs around $3,500 but if the test is recommended by a specialist it is usually covered by ...


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    Hereditary Breast Cancer. Approximately 7% of breast cancer and 11 - 15% of ovarian cancer cases are caused by mutations in the BRCA1 or BRCA2 genes.


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    Breast feeding can protect you against developing breast cancer.


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    National Hereditary Breast Cancer Helpline, Bakewell, United Kingdom. 3,524 likes 160 talking about this.

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    It could be your mom, sister, aunt or best friend. One out of 8 women will get breast cancer in her lifetime. A small subset of the women who get diagnosed ...

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    May 14, 2013 Myriad Genetics owns the genes that indicate breast-cancer risk and the pricey test could be costing lives

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    Frequently asked questions about genetic testing in general and how it specifically relates to breast and ovarian cancer risk.

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    What is breast cancer and ovarian cancer? Cells normally grow and divide only when they are needed to keep our bodies functioning properly. But sometimes, the ...

  • Subject: Genetic Testing for Hereditary Breast or Ovarian Cancer

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    DESCRIPTION: Several genetic syndromes with an autosomal dominant pattern of inheritance that feature breast cancer have been identified. Of these, hereditary breast ...